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These observed sex-dependent differences have been attributed to sex-dependent metabolic alterations such as the estrogen-dependent synthesis of phosphatidylcholines 88,89,90,91
The prevalence of MASLD has been escalating rapidly, demonstrating a consistent upward trend year on year, notably among younger individuals [9, 10]
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Cellular Energy Production Supports mitochondria and ATP generation
Binding GLP-1 receptors in pancreatic beta cells, enteroendocrine L-cells, and hypothalamic neurons, while simultaneously activating GIP receptors that potentiate insulin secretion and reduce glucagon output
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